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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
16.97
Human Site:
Y131
Identified Species:
31.11
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
Y131
E
P
D
D
A
R
D
Y
F
Q
M
A
R
A
N
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
Y131
E
P
D
D
A
R
D
Y
F
Q
M
A
R
A
N
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
Q113
N
E
S
F
A
R
I
Q
V
R
F
A
E
L
K
Dog
Lupus familis
XP_539016
855
96614
Y131
E
P
D
D
A
R
D
Y
F
H
M
A
K
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
Y127
E
P
D
D
A
R
D
Y
F
Q
M
A
R
E
N
Rat
Rattus norvegicus
NP_001101642
835
94323
Y127
E
P
D
D
A
H
D
Y
F
Q
M
A
R
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
H131
E
P
D
D
A
R
D
H
F
Q
M
A
K
A
N
Chicken
Gallus gallus
XP_419867
879
99691
Q135
D
P
E
E
A
R
D
Q
F
H
L
A
R
L
N
Frog
Xenopus laevis
NP_001082090
882
99060
Q132
D
L
D
E
A
R
E
Q
F
Q
F
A
R
L
N
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
H193
L
S
V
S
A
L
D
H
T
Q
G
S
R
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
P126
H
E
D
A
S
P
F
P
G
T
I
T
K
T
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
L112
T
Q
D
T
T
N
N
L
A
I
T
S
V
A
G
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
G99
S
S
H
S
T
L
F
G
R
Y
L
R
N
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
86.6
N.A.
93.3
86.6
N.A.
86.6
53.3
53.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
86.6
N.A.
100
80
73.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
77
0
0
0
8
0
0
70
0
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
70
47
0
0
62
0
0
0
0
0
0
0
0
% D
% Glu:
47
16
8
16
0
0
8
0
0
0
0
0
8
16
0
% E
% Phe:
0
0
0
8
0
0
16
0
62
0
16
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
8
% G
% His:
8
0
8
0
0
8
0
16
0
16
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
8
% K
% Leu:
8
8
0
0
0
16
0
8
0
0
16
0
0
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
8
0
0
0
0
0
8
8
62
% N
% Pro:
0
54
0
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
24
0
54
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
62
0
0
8
8
0
8
54
8
0
% R
% Ser:
8
16
8
16
8
0
0
0
0
0
0
16
0
0
8
% S
% Thr:
8
0
0
8
16
0
0
0
8
8
8
8
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _